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IRAP in Equine Osteooathritis

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By Dr. Bellefeuille, DVM, MS

Lameness due to joint disease is detrimental in the equine industry. Osteoarthritis and joint disease cause the largest economic impact in performance and aged horses. Over the last decade new advances in scientific therapies have been introduced to the equine market that allow veterinarians to treat the once thought of untreatable osteoarthritis and degenerative joint disease. Interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF) are two of the primary proinflammatory cytokines that initiate the destructive cascade of osteoarthritis leading to a vicious cycle of cartilage erosion/damage and lameness. Therefore, IL-1 and TNF are two of the most targeted cytokines to help slow and even stop the destructive process that occurs within joints during osteoarthritis. Autologous conditioned serum is produced by conditioning certain blood components to increase their production of components that counteract or interfere with the IL-1 and TNF pathways.
Our ability to condition a horse’s own blood into a product that can be injected back into joints has come a long way in the past few years. The most widely used autologous conditioned serum product is IRAP. IRAP stands for Interleukin-1 Receptor Antagonist Protein. It was developed to counteract IL-1 that is produced in the traumatized joint leading to cartilage damage and lameness. IRAP works by preventing the binding of IL-1 to its receptor, therefore blocking the damage and inflammation caused by IL-1. To read more pick up the April 2016 issue of NTFR.

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Equine

AQHA Horse of the Year

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By Krista Lucas Wynn

Each year, when the professional rodeo season wraps on Sept. 30, the Professional Rodeo Cowboys Association and Women’s Professional Rodeo Association announce the Nutrena Horse of the Year, presented by the American Quarter Horse Association, in each event. This is a prestigious award, voted on by the members of the associations. To be named Horse of the Year by fellow competitors is a high honor only a few achieve.

To read more, pick up a copy of the November edition of North Texas Farm & Ranch magazine, available digitally and in print. To subscribe by mail, call 940-872-5922.

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Equine

Tuff Enough: Tuff Hardman Wins Big At Cheyenne Frontier Days

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Tuf Hardman Wins At Cheyenne

By: Krista Lucas Wynn | Copy Editor

The name, “Daddy of ’em All,” instantly brings to mind the world’s largest outdoor rodeo and western celebration. Cowboys and cowgirls from all across the country dream of competing on the iconic Cheyenne arena dirt.

Every July, pro rodeo contestants travel to Cheyenne, Wyom. to vie for the title of champion of the Cheyenne Frontier Days. The rodeo is steeped in western tradition and celebrated the 125th year this summer. With nearly two weeks of rodeo action, fans watched bareback riding, calf roping, breakaway roping, saddle bronc riding, team roping, steer wrestling, barrel racing, bull riding, and steer roping.

Steer roper, Tuff Hardman, knew winning “the Dad” was a tall order, but with a good horse and a few prayers he left no doubt who the best steer roper at Cheyenne was when it was all said and done. After two rounds, Hardman qualified back for the finals tied for ninth place with a time of 30.8 seconds.

To read more, pick up a copy of the September issue of NTFR magazine. To subscribe by mail, call 940-872-5922.

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Country Lifestyles

Mandy Cleveland & Stable Strides Farm

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Stable Strides Farm

Utilizing the horse to human connection.
By: Hannah Claxton | Editor

Deep in the heart of Texas, both humans and horses at Stable Strides Farm in Pilot Point, Texas aer demonstrating just how big their hearts really are. Founded by Mandy Cleveland in 2001, Stable Strides Farm serves dozens of Equestrians with Disabilities and Veterans each week.


Deep in the heart of Texas, both humans and horses at Stable Strides Farm in Pilot Point, Texas aer demonstrating just how big their hearts really are. Founded by Mandy Cleveland in 2001, Stable Strides Farm serves dozens of Equestrians with Disabilities and Veterans each week.

“My boys have been riding since they were 18 months old, and for the first 17 years they had a leader and sidewalker. When we moved here, and Mandy started teaching them, she just said, ‘Let’s see what they can do,’ and they ride independently now,” Danielle Frank explained, whose two sons, Adison and Aiden, ride with Stable Strides Farm. “Mandy is amazing beucase she doesn’t place any limits on them, she always wants to see what they can do.”

It is her dedication to never setting limits that earned Cleveland a spot as a national finalist for the NSBA 2024 Dianne Eppers Cowgirls Reaching-Out-to-Community Award. The award was established by the NSBA Foundation to recognize cowgirls across the industry for their selfless contributions to the equestrian community.

To read more, pick up a copy of the September issue of the NTFR magazine. To subscribe by mail, call 940-872-5922.

(Photos Courtesy of Hannah Claxton)

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